In recent years, transnational criminal networks have built a web of influence throughout Southeast Asia to facilitate their illicit gambling, fraud and human trafficking operations. And while these networks emanate from several countries in the region — particularly Myanmar — their reach is global. In the United States alone, victims have already lost several billion dollars to scams. USIP’s Andrew Cheatham and Jason Tower discuss how these large-scale networks operate, how the 2021 military coup in Myanmar offered the networks a safe haven for their illicit activities, and how the United States can take the lead on addressing this issue.